Interestingly, a sub-stoichiometric expression of CK2β compared to CK2α in a subset of breast cancer tumors is correlated with the induction of hypoxia and epithelial to mesenchymal transition (EMT) markers, providing evidence that unbalanced expression of CK2 subunits may influence key cellular processes associated with epithelial cell plasticity in breast carcinoma progression (Deshiere et al., 2013; Golden and Cantley, 2014). This evidence concerns the gene CSNK2B and breast carcinoma.