Autosomal dominant polycystic kidney disease (ADPKD) is the most common genetic disorder of the kidney, caused by mutations in the PKD1 and PKD2 genes that encode for transmembrane proteins polycystin-1 (PC1) and polycystin-2 (PC2), respectively (Grantham, 2008). The gene discussed is PKD1; the disease is autosomal dominant polycystic kidney disease.