HSPG2 and neoplasm: Multivariate logistic regression analysis showed that tumor size (odds ratio [OR], 1.255, 95% confidence interval [CI], 1.091–1.444; p = 0.002), peripheral washout (OR, 4.891; 95% CI, 1.437–16.643; p = 0.011), and AFP ≥20 ng/ml (OR, 0.514; 95% CI, 0.291–0.910; p = 0.022) were independent variables associated with the MVI of PLC (Table 5).