As a result, 62 TF genes (log2 FC > 0.5, BH-adjusted P < 0.05) and 1693 target genes (log2 FC > 1.25, BH-adjusted P < 0.05) were identified as differentially expressed genes in CMS4 of CRC (Figure 1A). The gene discussed is TF; the disease is colorectal carcinoma.