PDCD4 and neoplasm: Superoxide dismutase (SOD), catalase and total antioxidation capacity (T-AOC) are decreased, whereas 8-Oxo-deoxyguanosine (8-Oxo-dG), a marker of inflammation, is increased with elevated miRNA-21- and decreased PDCD4 expression and correlates with tumour staging, lymph node metastasis and remote metastasis in gastric cancer (143).