GJA1 and central nervous system cancer: It has been demonstrated that TMs in 1p/19q non-co-deleted gliomas are frequently more and longer than those in 1p/19q co-deleted ones and the RNA-Seq gene expression data revealed that the gap junction protein Cx43 and core pathways driving neurite formation and the growth of neurite-like TMs are highly expressed in 1p/19q non-co-deleted gliomas (12).