To assess the relationship between the expression level of RPS3 in ACC and the prognosis of patients, a total of 73 patients with ACC (35 males and 38 females), aged 18~70 years (mean age 42 ± 8.5 years), were included in this study; 37 had high RPS3 expression, and 36 had low RPS3 expression. This evidence concerns the gene RPS3 and adrenal cortex carcinoma.