Interestingly, some of these genes, such as LEP, ALOX12, RARRES2, DLEU7, and FOXR1, have been reported to be associated with other hematologic malignancies, including AML, chronic lymphocytic leukemia (CLL), and B-cell lymphoma (15, 21–24). The gene discussed is ALOX12; the disease is B-cell chronic lymphocytic leukemia.