IL4 and neoplasm: Supplementary Table S2 in Appendix B lists the initial conditions that represent each of these scenarios. Many of these initial conditions are the same that were used in [24]. For the case of an initially high pro-tumor cell polarization, we used the M2 macrophage and Th2 cell concentrations predicted in the tumor microenvironment according to the mathematical model presented in [4], and the IL-4 and IL-10 concentrations used in [31].