Thus, trials are investigating whether immune-suppressing therapies such as interleukine (IL) 1 receptor antagonist (IL-1Ra) and anti–IL-6 could dampen the early cytokine storm, and conversely whether immune-stimulatory agents such as IL-7, granulocyte macrophage-colony stimulating factor (GM-CSF), and interferon gamma (IFN-γ) could reverse sepsis-induced immunosuppression (14). This evidence concerns the gene IFNG and Sepsis.