Multivariate logistic regression analysis showed that age >60 years old, history of cardiovascular and cerebrovascular diseases, dialysis age >12 months, systolic blood pressure >140 mmHg, blood phosphorus level >1.5 mmol/L, TG level >2.30 mmol/l, ADPN level <5 mg/L, hs-CRP level >10 mg/L, Hb level <120 g/L, SCr level >720 μmol/L, and ALB level <40 g/L were independent risk factors for cardiovascular and cerebrovascular events in patients with DN receiving maintenance hemodialysis (P < 0.05) (see Table 2 for details). The gene discussed is ALB; the disease is cerebrovascular disorder.