In these 137 patients, high expression of SFRP4 was found in 96 (70.07%) cancer tissues and 76 (55.47%) paracancerous tissues (Table 2), and SFRP4 expression was considerably elevated in cancer tissues compared to paracancerous tissues (P=0.012) (Figure 1(b)). The gene discussed is SFRP4; the disease is cancer.