CD4 and neoplasm: The correlation analysis between immune cells was conducted with Corrplot R, and results showed some strong tumor-immune cell interactions in HBV-related HCC; for example, T cells CD4 memory resting and plasma, T cells CD4 memory resting and CD8 T cell, T cells follicular helper and T cells CD4 memory resting, macrophages M2, and mast cells activated (Figure 8(c)).