STAT3 and Zika virus infectious disease: Inhibition of STAT3 by 17-AAG in hBMECs efficiently impaired JEV infection, which was not observed in MAPK/ERK inhibition by U0126, supporting that the MAPK/ERK pathway could contribute to the JEV life cycle, which is similar to the result in ZIKV infection (Sabino et al., 2021).