In recent years, the activated EGFR also appeared in response to viral infection, including IAV, PEDV, ZIKV, and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) (Yang et al., 2018; Klann et al., 2020; Sabino et al., 2021; Wang et al., 2021). This evidence concerns the gene EGFR and viral infectious disease.