Age, height, weight, BMI, hirsuties, acne, waist circumference, hip circumference, total testosterone (TT), sex hormone binding globulin (SHBG), double hydrogen testosterone (DHT), free testosterone (FT), fasting insulin (FINS) and fasting blood glucose (FBG) were compared between PCOS patients and healthy controls. The gene discussed is SHBG; the disease is polycystic ovary syndrome.