As for colon cancer, the cell apoptosis assay illustrated anti-apoptosis effect of the ethyl acetate extract of A. dahurica root (200 and 250 μg/ml, 48 h) on colon cancer HT-29 cells through p53-independent pathway (Zheng et al., 2016b). The gene discussed is TP53; the disease is malignant colon neoplasm.