MMP2 and melanoma: In murine melanoma B16F10 cells, the 70% ethanol extract of A. dahurica root (100 and 200 μg/ml for 24 h) was confirmed to inhibit the growth, migration, invasion and colony formation, while stimulating cell apoptosis via reducing the activity of matrix metalloproteinase-2 (MMP-2) and MMP-9 (Hwangbo et al., 2020).