GLP1R and type 2 diabetes mellitus: Though previous studies, including meta-analyses, have investigated the impact of DPP-4i, GLP-1 RAs, and SGLT-2i on the risk of fracture in patients with T2DM, their findings are not consistent (Su et al., 2015; Gamble et al., 2018; Adimadhyam et al., 2019; Cheng et al., 2019; Hidayat et al., 2019).