PIK3CA and cancer: Also, Cur targeted phosphatidylinositol 3-kinase (PI3K)/protein kinase B (AKT), Janus kinase/signal transducer and activator of transcription, and nuclear factor kappa B (NF-κB) pathways (Wong et al., 2021) in almost most cancer forms (El-Far et al., 2020a; Joshi et al., 2021).