In contrast, FDG5-AS1 and SNHG16 function as miRNA sponges for miR-520b and miR-4500, leading to increased expression of USP21 in oral squamous cell carcinoma and NSCLC, respectively, (Liu et al., 2020; Xu et al., 2020). Here, USP21 is linked to non-small cell lung carcinoma.