Some proteins related to an increased risk of cardiovascular disease are transported in microvesicles, including CD26, CD14, and cystatin C, the latter being a protein inhibitor of cysteine proteases (Dini et al., 2020; Peng, Liu & Xu, 2020; Vijay et al., 2018; Yamamoto et al., 2013; Chung et al., 2018). Here, CST3 is linked to cardiovascular disorder.