Pathway analysis showed that those TFs were involved mainly in transcriptional misregulation in cancer, hepatitis B, human T-cell leukemia virus 1 infection, viral carcinogenesis, kaposi sarcoma-associated herpesvirus infection, c-type lectin receptor signaling pathway, lipid and atherosclerosis, acute myeloid leukemia, hepatitis C, Th17 cell differentiation (P < 0.0001; Fig. S4B). This evidence concerns the gene CLEC4D and atherosclerosis.