Moreover, Hiatt et al. (2018) reported cases of de novo RALA germline variants causing Hiatt-Neu-Cooper neurodevelopmental syndromes (HINCONS) with the variation that included six missense variants of c.G73A, c.G73T, c.A383G, c.A389G, c.T469G, and c.C526T and one chromosomal microdeletion of c.472_474delGCT. This evidence concerns the gene RALA and Hiatt-Neu-Cooper neurodevelopmental syndrome.