Bonduelle et al. (2021) investigated 20 cases of mild malformations of cortical development with oligodendroglial hyperplasia in epilepsy (MOGHE) children using brain tissue sequencing. SLC35A2 somatic mutations were detected in 9/20 (45%) patient brains, while the germline variants of the SLC35A2 gene led to developmental and epileptic encephalopathies. The gene discussed is SLC35A2; the disease is Epileptic encephalopathy.