PLCG1 and infection: Further it appears possible that Salmonella inhibiting PLCG1 phosphorylation is part of the unique survival strategy of paratyphoid Salmonella in poultry that minimizes host defenses mechanisms (disease resistance) during the initial infection and then further uses the inhibition of PLCG1 activity as part of the immunometabolic reprogramming that converts host defense strategy to disease tolerance.