We have further shown that IFN-γ can activate in vitro heterophil functional activity against Salmonella (Kogut et al., 2001; Kogut et al., 2005) and the presence of IFN-γ and IL-2 in a S. Enteritidis immune cytokine cocktail protects day-old chicks against Salmonella infections mediated by activated heterophils (Kogut et al., 1996; Verduzzo et al., 2009). Here, IL2 is linked to Salmonella Infections.