IL-6 overexpression is constantly detected in PCa patients (Nakashima et al., 2000) and abnormal expression of IL-6 can activate the JAK-STAT signaling pathway and affect tumor growth by autocrine or paracrine loops (Aaronson and Horvath 2002; Culig et al., 2005; Aaronson et al., 2007). The gene discussed is IL6; the disease is neoplasm.