ACKR3 and myocardial infarction: Although ACKR3 is also expressed in cardiac fibroblasts, which are involved in cardiac repair after MI, no impact on cardiac function was observed in infarcted mice with conditional ACKR3 deletion in fibroblasts (Col1a2-CreERT2 x Cxcr7flox/flox model) (68) (Figure 1).