To our knowledge, this is the first meta-analysis being done to date in the academic field to investigate the relationships of the rs1801282 and rs3856806 polymorphisms in PPARγ gene with obesity indexes, although there was a meta-analysis investigating the associations of the two polymorphisms with circulating lipid levels by Li and colleagues (156) in 2015. This evidence concerns the gene PPARG and obesity due to melanocortin 4 receptor deficiency.