Finally, the mechanism underlying the retinal dystrophy in ahi1 mutants is not definitely determined, but the described dysmorphic outer segments, aberrant disk stacking/orientation and accumulation of vesicular material with normal connecting cilium morphology could indicate a similar role in vesicular fusion as for Cc2d2a (Lessieur et al., 2017). Here, AHI1 is linked to Retinal dystrophy.