To decipher the potential mechanisms of risk score, we performed GSEA and found that high-risk patients were enriched not only for pro-cancer-related pathways such as mTOR and P53 pathways, but also for immune- and stromal-related processes such as inflammatory response, IFNγ response, TNFα signaling, and cell adhesion (Figures 7A,B). Here, TNF is linked to cancer.