The level of another microRNA, miR-590-3p, was increased in glioma tissues and radioresistant glioblastoma cells; miR-590-3p was shown to promote radioresistance by directly inhibiting the tumor suppressor LRIG1 (leucine rich repeats and immunoglobulin like domains 1) [21]. This evidence concerns the gene LRIG1 and glioblastoma.