ALK and breast cancer: TP63 is a prognostic gene in breast cancer patients [26], lung squamous cell carcinoma [27], pancreatic cancer [28], skin cutaneous melanoma [29], anaplastic lymphoma kinase-negative anaplastic large cell lymphoma [30], etc. STEAP3 is a metal reductase, encoding a transmembrane protein that functions as an iron transporter and coordinates the regulation of iron homeostasis [31].