In addition to comparing the expression of LGG, we also performed extended analysis of the expression of Pan in order to find out whether PROK1 and PROK2 are similar to LGG in other cancers, and we found that there were significant differences in the expression of Pan cancer and adjacent tissues, which confirmed that there were co-expression in different tissues, but there were significant differences in expression pattern [31]. This evidence concerns the gene PROK2 and cancer.