Among all the lncRNAs, we noticed that lncRNA FGD5-AS1 acted as an oncogene to facilitate the development of multiple cancers, such as colorectal cancer (CRC) [8], oral cancer [9], non-small-cell lung cancer (NSCLC) [10], and esophageal squamous cell carcinoma (ESCC) [11]. Here, FGD5 is linked to esophageal squamous cell carcinoma.