IL37 and psoriasis: In this study, based on the results of PASI 75, PASI 90, and PASI 100, we observed that interleukin-23-targeted drugs had a more significant effect on patients with moderate-to-severe psoriasis, with patients in the trial group significantly outperforming the control group in terms of improvement in PASI 75, PASI 90, and PASI 100.