IRF8 and hepatocellular carcinoma: Furthermore, analysis of four HCC cohorts (“Chen Liver” data set, “Roessler Liver” data set, “Roessler Liver 2” data set, and “Wurmbach Liver” dataset) also revealed the downregulation of IRF8 expression in HCC tissues, which was further confirmed by meta‐analysis based on the ONCOMINE database (Figure S1D–H).