While only the FOXM1, PYROXD1, hTERT and MCTP1 genes were overexpressed in CRC tumor tissues relative to the normal adjacent tissues at all the stages, but FOXM1, PYROXD1, hTERT, PIM3, BMI1, PPARA and MCTP1 were found to have stage-dependent expression. The gene discussed is PYROXD1; the disease is colorectal carcinoma.