miR-182 is highly expressed in exosomes derived from gallbladder cancer, which can increase the expression level of N-cadherin and MMP2 by targeted inhibition of reversion-inducing-cysteine-rich protein with kazal motifs (RECK) and, finally, significantly promote the metastasis and invasion of gallbladder cancer cells [27]. The gene discussed is MMP2; the disease is gallbladder cancer.