The consequences indicated there were seven prognostic genes with high expression negatively relevant to surviving rate of ccRCC sick persons (CASP3, CASP4, CASP5, AIM2, CASP9, GSDMB, and PYCARD), and two prognostic genes with high expression positively correlated with surviving rate of ccRCC sick persons (CHMP3 and CHMP4C), P < 0.05. This evidence concerns the gene CASP4 and nonpapillary renal cell carcinoma.