Nine of these genes (NLRP2, TP63, CYCS, CASP9, IL1A, CHMP2B, CHMP4C, CHMP3, and IL1B) were downregulated, while 32 genes (HMGB1, CHMP4B, IRF2, CHMP2A, CHMP6, TP53, GPX4, CASP3, PLCG1, NOD1, GSDMD, CASP8, IL18, CHMP4A, IRF1, BAX, NLRP1, CASP4, NLRP3, GSDMA, NLRP6, CASP1, NLRC4, GSDMB, PYCARD, GSDMC, NLRP7, NOD2, GZMB, CASP5, AIM2, and GZMA) were upregulated in cancer tissues. Here, CHMP4A is linked to cancer.