TF and myocardial infarction: Taken together, the correlation data suggest that, while measurement of thrombin and FX levels could guide the selection of the type of direct oral anticoagulants (DOAC), patients with higher levels of circulating TF might benefit from higher doses of DOACs, therefore limiting the amplitude of the hemostatic response and potentially reducing both the risk of forming an occlusive thrombus and risk of recurrent MI.