CD4 and atherosclerosis: In contrast to B2 cells, however, these cells can diminish inflammation in atherosclerosis by antibody-secretion (116) blocking the uptake of oxLDL (109) and declining the number of associated CD4+ T cells in case of B1 cells (117) and excretion of anti-inflammatory cytokines like IL-10, IL-35 and TGFß in B regs (118).