SP1 and cardiovascular disorder: In recent literature, TFs like SRY-box transcription factor 9 (SOX9), Sp1 transcription factor (SP1), GATA binding protein 6 (GATA6), forkhead box O1 (FOXO1), and BTB domain and CNC homolog 1 (BACH1) have been studied to explore their roles in the occurrence and development of various cardiovascular diseases (11–17).