Several correlations between morphological signs and cytogenetic and molecular abnormalities have been identified in acute myeloid leukemia (AML), including the well‐known “faggot cells” in acute promyelocytic leukemia with PML – RARA and abnormal eosinophilic bone marrow proliferation in AML with inv(16) or t(16;16); CBFB – MYH11. This evidence concerns the gene RARA and acute myeloid leukemia.