It has been reported that BMSCs derived from bone marrow have immunomodulatory effects in tissue microenvironment, BMSCs exosomes derived from bone marrow can significantly reduce the release of IL-10 and TGF-β from peripheral blood mononuclear cells of asthma patients than BMSCs themselves, thus alleviating the symptoms of asthma attack. This evidence concerns the gene TGFB1 and asthma.