NLRP3 and gout: Figure 5B listed the top 20 keywords with the strongest citation burst, and the keywords that the burst period lasted until now were ULT, expression, mechanism, nlrp3 inflammasome, oxidative stress, asymptomatic hyperuricemia, and acute gouty arthritis. Figure 5C showed a visualization of keywords that co-occurred more than 5 times in the gout research. The size of the node was proportional to the frequency of keyword occurrences, and a thicker line between two nodes was associated with a higher frequency of their co-occurrence (14, 15).