After multiple screenings, a total of 10 hub genes related to NASH (KDR, FYN, RAC1, MAPK1, ERBB2, CDKN1A, HSPA4, SMAD2, MCL1, and ESR1) in the circRNA–miRNA–mRNA network were identified. This evidence concerns the gene RAC1 and metabolic dysfunction-associated steatohepatitis.