Then, a subnetwork with 10 nodes and 31 edges was selected, which revealed the critical roles of the ten genes (KDR, FYN, RAC1, MAPK1, ERBB2, CDKN1A, HSPA4, SMAD2, MCL1, and ESR1) in NASH (Figure 6). The gene discussed is ERBB2; the disease is metabolic dysfunction-associated steatohepatitis.