Myeloid-derived Suppressor Cells (MDSCs) are recruited by ETBF infection which inhibits the activity of cytotoxic CD8 + T cells and ETBF induces the expression of matrix metalloproteinase 9 (MMP9) and vascular endothelial growth factor A (VEGFA) thus triggering CXCL1 and CXCL2 via IL-17 87, 88 (Fig. 4). Here, MMP9 is linked to infection.