ICAM1 and breast angiosarcoma: Of particular relevance to this review were the findings presented almost 30 years ago demonstrating that ICAM1 is overexpressed in extra- and intra-hepatic bile ducts of BA patients (70, 71) and, in 2008, Arikan et al. reported that the A allele of SNP (rs1799969) in ICAM1 was positively correlated with BA (27).