The BRAF mutation is the most common mutant gene in melanoma and co-occurred with CCND1 amplification in 0.33% (1/302), 1.91% (7/367), and 1.14% (4/350) of tumor samples from the Geneplus, TCGA, and MSKCC cohorts, respectively. The gene discussed is CCND1; the disease is neoplasm.