In summary, the clinical parameters influencing the long-term prognosis in AAV patients included age, pathological categories (MPA, GPA, and other types), ANCA IIF staining patterns (negative or positive for p-ANCA and/or c-ANCA), serum ANCA types (negative or positive for MPO and/or PR3), BVAS, Scr, GFR, NLR, RBC, Hb, lymphocyte, TP, albumin, A/G, UA, CRP, ESR, and C3. The gene discussed is C3; the disease is anti-neutrophil cytoplasmic antibody-associated vasculitis.