Some preclinical studies have suggested an elevated microglial-derived neuroinflammmation in varied neuropsychiatric disorders by using 18-kDa translocator protein positron emission tomography, which is expressed on activated microglia to quantify central neuroinflammation and has been considered as a promising new validating microglial inflammatory biomarker in psychiatric and neurological disorders (31–33). Here, TSPO is linked to nervous system disorder.