While a question remains as to what extent this may impact IBD pathogenesis (65), it is notable that such a switch was additionally observed in the population of ILC precursors (ILCp); an increase in NKp44+ and CD56+ ILCp was detected in CD patients, coupled to a decrease in their corresponding naïve CD45RA+ ILCp (64). The gene discussed is NCR2; the disease is inflammatory bowel disease.